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LIBERO ITS - The World's First Wireless Electronic Time and Temperature Indicator
The simplest and most affordable indicator for continuous temperature monitoring and calculating a stable budget for a pharmaceutical product or clinical study throughout the supply chain.
End-to-end time and temperature monitoring
LIBERO ITS is an innovative electronic multi-stage indicator with revolutionary reading technology. It is a device for continuous temperature monitoring and calculating the remaining stability budget of valuable products throughout the supply chain. It is thin and small enough to be placed on any sales unit or even on a single product. It is durable enough to remain on the product for its entire shelf life of up to 4 years. LIBERO ITS manages up to 6 alarm levels of deviation. The alarm status is always visible by displaying green = OK or red = ALARM. Watch the video to see how LIBERO ITS solves the challenges of a long, decentralized supply chain.
No more guessing about product loss - you have the proof!
If the product's specific stability budget is used, LIBERO ITS will display a red LED: Alarm! In most cases, the product must be discarded. But suppose the product is not under your direct control. How do I notify the person responsible for the product? How is the status recorded? Furthermore, how can I archive this document in a safe and compliant way?
LIBERO ITS offers a smartphone app to download summary statistics including time stamps, maximum/minimum temperatures, and tour times for each temperature zone. Use the app to add information, notify product owners via email and securely archive survey results. In addition to supporting you in fault analysis (whose fault is it?), the database will also help you to analyze your products. the database will also help you run a compliant and efficient cold chain.

Compliance and Certification
World Health Organization PQS E006
WHO certified for performance, quality and safety.
NIST-Traceable Correction Certificate
Proof that LIBERO ITS meets the highest international quality standards.
GAMP5 Verification
Proven technology that meets regulatory requirements and gives you peace of mind
IATA compliant
No battery statement or paperwork required
How to use LIBERO ITS
LIBERO ITS has a simple operating procedure. After the electronic indicator is applied at the point of packaging, it is securely attached to the unit-level product through as many warehouses, handling procedures and transportation methods as the product faces. At any of these transportation or storage points, the indicator can be read to give product status (alarm/no alarm). Finally, the statistics are downloaded to a smartphone or LIBERO Cloud.
1. Break the tab to open the tab.

Break the label and attach LIBERO ITS to products with self-adhesive backing.
2. read data wirelessly

Monitor for 4 years and check LEDs: Green = Normal, Red = Alert
3. Upload PDF report to database

Download statistics to your smartphone when an alarm occurs.
Select the LIBERO ITS that is right for your application.
reefer
- LIBERO Gx
- ECOLOG-PRO xG
- ECOLOG-PRO RBR and Sensors

- +2 °C to +8 °C (strict profile)
- 12 months shelf life
- Up to 5 years of battery life
- 100% (NIST-Traceable) Calibration
- Available in boxes of 10 or boxes of 400
- No stable budget
Room temperature
- Artworks
- TATS materials
- High-value food
- End-to-End Pharmaceuticals

- +15 °C to +25 °C (strict configuration)
- 12 months retention period
- Up to 5 years of battery life
- 100% (NIST-Traceable) Calibration
- Available in boxes of 10 or boxes of 400
- No stable budget
zero degree
- Artworks
- TATS materials
- High-value food
- End-to-End Pharmaceuticals

- Above 0 °C
- 12 months shelf life
- Up to 5 years of battery life
- 100% (NIST-Traceable) Calibration
- Available in boxes of 10 or boxes of 400
- No stable budget
WHO Type 1
- Type 1 vaccine

- -0.5 °C to +30 °C
- 12 months retention period
- Up to 4 years of battery life
- 100% (NIST-Traceable) Calibration
- Available in boxes of 10 or boxes of 400
- Stabilizing the Budget
WHO Type 2
- Type 2 vaccine

- Up to +10 °C
- 12 months shelf life
- Up to 4 years of battery life
- 100% (NIST-Traceable) Calibration
- Available in boxes of 10 or boxes of 400
- Stabilizing the Budget
Customized Profiles
- Customizable for any application

- Create your own profile
- 12 months shelf life
- Up to 4 years of battery life
- 100% (NIST-Traceable) Calibration
- From 3200 pieces
- Up to 6 Stability Budget Alert Levels
What our customers say about LIBERO ITS
The personalization of pharmaceuticals leads to personalized product programs and even personalized distribution. As a result, temperature monitoring at the batch level is no longer sufficient. For these cases, temperature monitoring on a single project level is required. LIBERO ITS offers everything needed in terms of size, cost and functionality.
Director, Global Supply ChainMultinational Biopharmaceutical Company
As trial sponsors meet the needs of their patients for at-home clinical trials, we are faced with the challenge of navigating direct-to-patient distribution. Using LIBERO ITS ensures that we monitor the temperature of the product until the patient is dosed and maintains the integrity of the clinical trial.
Clinical Trial ManagerClinical Research Corporation
LIBERO ITS beats the competition in every way.
A Time-Temperature Indicator (TTI) is a smart label that is affixed directly to a product to show the cumulative time-temperature history of the product over its life cycle. The first versions of time and temperature indicators were chemical indicators, mainly used in the food industry. These chemical indicators work by aligning the physical changes in the indicator with the rate of degradation of the food product. Thus, the indicator can help indicate possible food degradation.
LIBERO ITS can functionally override and replace any other chemical indicator, freeze indicator or multi-level indicator. When produced in large quantities, LIBERO ITS is cost-competitive with expensive chemical indicators and is less expensive than any other electronic multi-level indicator or freeze indicator.
Common Electronic Indicator
- Larger, limited statistical electronic readout devices.

- GAMP5 Validation and Traceable ID Numbers
- Connects directly to kit with self-adhesive backing
- No infrastructure, no training
- Intuitive status display (is it working?)
- Safe and easy start
- Accurate temperature sensors
- Low cost at the kit level (<$5)
- Thin (< 3 mm) & Small Kit Levels
- Tracking the Remaining Stability Estimate
- Typical kit life (up to 4 years)
- NIST Traceable Calibration Certificate
- Record and archive status
- Tracking Statistics
- Retain the entire measurement line for further analysis.
LIBERO ITS
- "Smart" electronic indicators with built-in stability budgets and complete statistical readings.

- GAMP5 Validation and Traceable ID Numbers
- Connects directly to kit with self-adhesive backing
- No infrastructure, no training
- Intuitive status display (is it working?)
- Safe and easy start
- Accurate temperature sensors
- Low cost at the kit level (<$5)
- Thin (< 3 mm) & Small Kit Levels
- Tracking the Remaining Stability Estimate
- Typical kit life (up to 4 years)
- NIST Traceable Calibration Certificate
- Record and archive status
- Tracking Statistics
- Retain the entire measurement line for further analysis.
Customized Profiles
- Customizable for any application

- GAMP5 Validation and Traceable ID Numbers
- Connects directly to kit with self-adhesive backing
- No infrastructure, no training
- Intuitive status display (is it working?)
- Safe and easy start
- Accurate temperature sensors
- Low cost at the kit level (<$5)
- Thin (< 3 mm) & Small Kit Levels
- Tracking the Remaining Stability Estimate
- Typical kit life (up to 4 years)
- NIST Traceable Calibration Certificate
- Record and archive status
- Tracking Statistics
- Retain the entire measurement line for further analysis.
Request a free sample of LIBERO ITS today!
Click below to get your working sample of the world's only intelligent electronic temperature (TTI) data monitoring metric used in the pharmaceutical supply chain and directly in patient clinical trials.

- Choose from a variety of popular standard configurations
- Read unique and stable budgets via smartphone apps
- 4 years battery life
- Fully compliant and NIST traceable
Application of LIBERO ITS
Professional technical support from HONGKEI to help you succeed in your project.
As a provider specializing in machine vision and optoelectronic inspection solutions, Avision is also committed to providing you with a range of paid technical services related to this product, aiming to help you succeed in your project in the most cost-effective way. Please contact us if you need technical services related to this product!